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| Torres,AFC; Dantas,RT; Menezes,RRPPB; Toyama,MH; Filho,ED; Oliveira,MF; Nogueira,NAP; Oliveira,MR; Monteiro,HSA; Martins,AMC. |
| Some snake venom proteins present enzymatic activities, such as L-amino acid oxidase (LAAO). The aim of this paper was to investigate the effect of Bothrops leucurus total venom (BleuTV) and its fraction LAAO (BleuLAAO) on bacteria, yeast, and promastigote forms of Leishmania amazonensis and Leishmania chagasi, and epimastigote forms of Trypanosoma cruzi. BleuTV was isolated with a Protein Pack 5PW® (Waters Corporation, USA), and several fractions were obtained. BleuLAAO was purified to high molecular homogeneity, and its N-terminal amino acid sequence shared a high degree of amino acid conservation with other LAAOs. BleuTV inhibited Staphylococcus aureus growth in a dose-dependent manner, with a minimum inhibitory concentration (MIC) of 25 μg/mL, which... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: L-amino oxidase; Bothrops leucurus; Antimicrobial activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000400012 |
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| de Oliveira, Jeison Saturnino; Santos, Daiana do Carmo; Guimarães, Adriana Gibara; Dias, Antônio Santos; Estevam, Charles dos Santos; de Lucca Júnior, Waldecy; Maria, Durvanei Augusto; Melo, Paulo de Assis; Araújo, Adriano Antunes de Souza; Quintans Júnior, Lucindo J.. |
| O ofidismo é um problema de saúde pública no mundo, especialmente nos países tropicais. O objetivo deste trabalho foi investigar os mecanismos envolvidos no efeito do extrato hidroetanólico da entrecasca da Abarema cochliacarpos (EAc) na lesão muscular induzida pelo veneno de Bothrops leucurus. Foram utilizados camundongos Swiss machos (28-32 g; n=6 por grupo), que receberam injeção perimuscular do veneno Bothrops leucurus (BlV – 1 mg/Kg/pata – Volume 50 μl) no membro posterior direito e foram tratados por via oral (v.o.) com veículo (solução salina) ou EAc (100, 200 ou 400 mg/kg). Na hipernocicepção mecânica, os animais foram avaliados nos tempos 2, 4 e 6 horas, utilizando o analgesímetro digital (Von Frey). Na atividade edematogênica, os animais foram... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops leucurus; Abarema cochiliacarpos; Ofidismo; Lesão muscular. |
| Ano: 2015 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/24829 |
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| Grego,K.F.; Alves,J.A.S.; Albuquerque,L.C. Rameh de; Fernandes,W.. |
| The hematological values for the specie Bothrops leucurus, recently captured from nature, were determined from blood samples of 29 snakes (11 males and 18 females). The performed hematological tests were: total red blood cell count (TRBCC), total white blood cell count (TWBCC), total trombocyte blood cell count (TTBCC); packed cell volume (PCV); hemoglobin content; and mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). The mean values for TRBCC was 4.23cellsx10(5)/mm³, for TWRCC was 8.92cellsx10³/mm³ and for TTBCC was 8.60cellsx10³/mm³. The mean for packed cell volume was 22.3%. The intraerythrocytic hemoparasite Hepatozoon sp was found on 58.6% of the studied animals. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cobra; Bothrops leucurus; Hematologia; Hemoparasitos. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600040 |
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